The Magpies' head coach felt that last weekend's draw at Watford - where his side had several opportunities to win the game - was "arguably our best performance of the season," and has stayed loyal to the same team at Molineux.
And it's the same bench, too, with Elliot Anderson joining up with the squad after scoring for the under-23s in their 4-1 win against Middlesbrough's second string on Friday evening.
Karl Darlow makes his third straight start in goal, with Javier Manquillo and Matt Ritchie continuing as full-backs and Ciaran Clark partnering stand-in skipper Federico Fernández in central defence.
Isaac Hayden will play in midfield alongside Sean Longstaff, fresh from his goal at Vicarage Road seven days ago, while Joe Willock, Joelinton, Allan Saint-Maximin and Miguel Almirón are the attackers as United look to get their first win of the campaign.
As well as teenager Anderson, the substitutes are Mark Gillespie, Emil Krafth, Jamal Lewis, Fabian Schär, Jeff Hendrick, Ryan Fraser, Dwight Gayle and Jacob Murphy, who scored in this fixture last season.
Newcastle United: Karl Darlow, Javier Manquillo, Federico Fernández, Ciaran Clark, Matt Ritchie, Isaac Hayden, Sean Longstaff, Joe Willock, Miguel Almirón, Allan Saint-Maximin, Joelinton.
Substitutes: Mark Gillespie, Emil Krafth, Jacob Murphy, Fabian Schär, Jamal Lewis, Jeff Hendrick, Elliot Anderson, Ryan Fraser, Dwight Gayle.