As a result, the game will move to Sunday, 5th May with a 4.30pm (BST) kick-off.
The match - which is scheduled to be United's last home game of the season - will be shown live on Sky Sports.
The clash against Jürgen Klopp's men is subject to further movement depending upon Liverpool's participation in the Champions League.
Should the Reds overcome FC Porto in the last eight to reach the semi-final stage, the fixture could be rescheduled again.