Magpies defender Dan Burn became his team's latest injury victim during the 1-0 Premier League win over Arsenal on Saturday, with a host of other first team players also unavailable for the game at Signal Iduna Park.

And Howe has opted to bring Tino Livramento, Lewis Hall and Joe Willock - who all impressed in the 3-0 Carabao Cup win at Manchester United just under a week ago - into the starting line-up for the fixture against the German giants.

Nick Pope continues in goal, with Hall coming in for Burn at left back, Jamaal Lascelles and Fabian Schär in the middle of the backline and Kieran Trippier at right back.

Sean Longstaff, Bruno Guimarães and Willock line up in midfield, with Livramento and Joelinton looking to provide support for frontman Callum Wilson.

Howe has named eight substitutes for the contest with Edin Terzić's men, with Miguel Almirón and Anthony Gordon - who made way for Livramento and Willock - both included, along with goalkeepers Martin Dúbravka and Loris Karius.

Paul Dummett adds extra experience to the bench, while youngsters Lewis Miley, Lucas De Bolle and Ben Parkinson are also named.

Newcastle United: Nick Pope; Kieran Trippier, Jamaal Lascelles, Fabian Schär, Lewis Hall; Sean Longstaff, Bruno Guimarães, Joe Willock; Tino Livramento, Callum Wilson, Joelinton.

Substitutes: Martin Dúbravka, Loris Karius, Paul Dummett, Lewis Miley, Lucas De Bolle, Miguel Almirón, Anthony Gordon, Ben Parkinson.