Fans heading to the Wolves game (kick-off 4.30pm GMT) can alight at Haymarket, but after the match they need to use St James, Monument or Central.
They will not be able board Metro services at Haymarket at full time.
Nexus, the public body which owns and manages Metro, has apologised to customers for the inconvenience caused.
Extra Metro staff will be on duty at Haymarket to assist with customer flow through the station.
There are three escalators at Haymarket Metro station. One is out of use due to long term total replacement scheme, while the other two have experienced recent faults which Nexus is working to rectify.
One escalator there is back now in service, hence the station being exit only, Nexus said.