And club partners BoyleSports have a fantastic football betting offer for the Toon Army ahead of the 8pm (GMT) kick-off.
The visitors will be facing a Premier League side for the first time in the competition this season having knocked out three lower-league opponents to reach the last eight, while top-flight opposition has proved no obstacle to the Magpies in the previous two rounds as they remain firmly in the hunt for the first silverware of the season.
The sides met as recently as Boxing Day, when the Magpies hit three first-half goals to record a 3-0 victory in their first league match after the World Cup. Before the international break, midfielder Miguel Almiron bagged seven goals in nine games and he carried on where he left off by finding the net just seven minutes into the festive fixture against the Foxes.
Now the top scorer for Newcastle this season features in this week's BoyleSports BetBuilder, which allows supporters to customise their own football bets by combining multiple selections into one single bet.
Get Newcastle To Win, Both Teams To Score + Almiron To Score First at 12/1.
For the latest betting news, tips, predictions and opinions, head to the BoyleSports blog every day.
* Prices subject to fluctuation. T&Cs apply
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