Peter Beardsley's side are currently third in the table and unbeaten at home in the league this term - but Wolves could overtake them with victory at Whitley Park.
The Black Country side, managed by former Magpies favourite Scott Sellars, were 4-1 winners when the two teams met at Molineux in October.
But United have only lost two league games since and the likes of Daniel Barlaser (who scored in this fixture last season), Stuart Findlay and Yasin Ben El-Mhanni have all made their first-team debuts in recent weeks.
Goalkeeper Rob Elliot is likely to play. Admission is free for season ticket holders and Members, otherwise it's £3 for adults and £1 concessions.