The 31-year-old scored the game's only goal at St. James' Park to help the Magpies to a third successive Premier League win, but had to be substituted early in the second half after sustaining a foot injury.
Trippier underwent an x-ray immediately after the game and scans have shown a fracture to the fifth metatarsal bone in his left foot.
Everyone at the club wishes Kieran a speedy recovery.