The game - which takes place at the Red Dragons' Racecourse Ground on Tuesday, 5th September (kick-off 19:30 BST) - is an all-ticket fixture for away supporters, meaning fans must buy their ticket from Newcastle United in advance.
The club have been allocated 300 tickets and they went on sale at 10am on Wednesday, 30th August, priced at £10 for adults and £5 for under-18s and over-65s. Please note the club's away points system is not in operation for this fixture.
Wrexham, who are owned by Hollywood actors Ryan Reynolds and Rob McElhenney, were promoted to the EFL after winning the National League title last term. Their squad includes Ben Tozer, who made two appearances for the Magpies in the 2009/10 season, and Elliot Lee, son of former United favourite Rob.
Tickets are on sale now from book.nufc.co.uk.