Manquillo comes in for DeAndre Yedlin, the young Spaniard deployed at right back for the first time since September’s 1-0 win at Swansea City.

The rest of the Magpies’ back four is unchanged from Tuesday’s 2-2 draw against West Bromwich Albion, while Karl Darlow again starts in goal.

Diamé partners Mikel Merino in central midfield, with Jacob Murphy and Matt Ritchie again starting out wide.

Up front, Gayle – who did not feature against the Baggies at all – has been chosen to lead the line, with Ayoze Pérez providing support in the No. 10 role.

Forwards Joselu and Aleksandar Mitrović have both been named on the substitutes’ bench, as well as Rolando Aarons, who has figured in United’s last two away games.

Newcastle United: Karl Darlow, Javier Manquillo, Florian Lejeune, Ciaran Clark, Chancel Mbemba, Matt Ritchie, Mikel Merino, Mohamed Diamé, Jacob Murphy, Ayoze Pérez, Dwight Gayle.

Substitutes: Rob Elliot, DeAndre Yedlin, Isaac Hayden, Jonjo Shelvey, Rolando Aarons, Aleksandar Mitrović, Joselu.