With Paul Dummett and Federico Fernández dropping out, Clark replaces the latter in the heart of the backline, with Kenedy moving from the wing to left back.

Atsu takes up the Brazilian’s place on the flank, with Joselu coming in for Salomón Rondón – who lasted just 45 minutes against Crystal Palace at Selhurst Park last week.

Ayoze Pérez will start just off his fellow countryman, with Mohamed Diamé and Jonjo Shelvey again playing together in central midfield.

Martin Dúbravka, DeAndre Yedlin, Jamaal Lascelles and Matt Ritchie all take up their regular positions, with Fabian Schär, Isaac Hayden and Sean Longstaff all returning to the Magpies’ bench.

The latter has yet to figure in the Premier League yet, having made his United debut in last month’s Carabao Cup defeat to Nottingham Forest.

Newcastle United: Martin Dúbravka, DeAndre Yedlin, Jamaal Lascelles, Ciaran Clark, Kenedy, Matt Ritchie, Mohamed Diamé, Jonjo Shelvey, Christian Atsu, Ayoze Pérez, Joselu.

Substitutes: Karl Darlow, Javier Manquillo, Fabian Schär, Isaac Hayden, Sean Longstaff, Jacob Murphy, Yoshinori Muto.