Wednesday 13th DecemberNewcastle United vs AC MilanSt. James' ParkKick-off 8pm GMT
The Dutch official - who also works as a part-time police inspector - will be tasked with keeping order on Tyneside as both sides look to secure their passage through to the knockout round.
The experienced Makkelie is a regular in European competition, having taken charge of the UEFA Europa League final in 2020 as Sevilla beat Inter Milan.
The 40-year-old also has a number of major international tournaments under his belt, having refereed at EURO 2020 and the 2022 World Cup.
Makkelie has had plenty of appointments as a VAR too, including in the 2018 World Cup final and 2019 Champions League final.
2023/24 stats
Games (all competitions): 16Yellow cards issued: 56Red cards issued: 2
Assistants
Assistant referees: Hessel Steegstra and Jan De VriesFourth official: Allard LindhoutVAR: Rob DieperinkAssistant VAR: Clay Ruperti