The Magpies will visit the country's capital, Riyadh, from 4th-10th December, and will face Saudi Pro League champions Al-Hilal in a friendly fixture on 8th December (venue and kick-off time TBC).
Eddie Howe's side previously travelled to Saudi Arabia in January 2022, visiting Jeddah and recording a 2-1 friendly victory over Al-Ittihad.
On their return to Premier League action, United subsequently won five of their next six matches as part of a nine-game run without defeat.
Eddie Howe said: "The break for the World Cup gives us the opportunity for a mini pre-season ahead of a crucial part of the season, and I'm pleased to have finalised our plans.
"Our trip to Jeddah in January was pivotal for us last season. It galvanised the group, and the hard work the players put in was rewarded in performances and results on our return.
"We will have access to world-class facilities as refurbishments at our own training ground continue, and we look forward to facing Al-Hilal and playing in front of our growing numbers of supporters in the region."
Al-Hilal is one of Saudi Arabia's most decorated clubs, winning the last three consecutive Saudi Pro League titles.
Further information on how to watch Al-Hilal v Newcastle United will be confirmed in due course, while nufc.co.uk, NUFC TV and the club's official social media channels will provide supporters with exclusive content throughout the trip.