Newcastle United, along with the rest of the clubs from the Premier League and Championship, enter the competition at this stage.
The Magpies will be ball number 28 and the draw will be shown live on BBC Two and BT Sport from 7pm (UK time).
Supporters can also check nufc.co.uk and the club's social media channels to discover Newcastle's opponents.
Newcastle will be hoping to fare better at this stage than they have in recent years. Last term, the Magpies beat Birmingham City after a replay, but lost at Watford in 2015/16, against Leicester in 2014/15, to Cardiff in 2013/14 and away to Brighton & Hove Albion in 2012/13.