The Magpies trained at the impressive facility at the same time as Burnley, with the two clubs splitting their squads to take part in two concurrent 11 v 11 sessions.
Two evenly-split United line-ups played against experienced and youthful Clarets sides respectively before switching opposition after 45 minutes.
The men in black and white prevailed in each of their respective halves, with a team captained by Jamaal Lascelles beating a youthful Burnley 4-1 over 45 minutes with goals from Joe Willock (2), Elliot Anderson and Miguel Almirón.
Almirón was back on the scoresheet against Burnley's stronger line-up after a short break, rounding off a 2-1 scoreline after Clarets left-back Ian Maatsen had cancelled out Callum Wilson's clinical opener.
Meanwhile, a United XI captained by Dan Burn prevailed 1-0 against an experienced Burnley side led up top by Ashley Barnes and Jay Rodriguez - Allan Saint-Maximin getting the only goal from close range.
After the break, Matt Ritchie and Jacob Murphy were on the scoresheet against a younger-looking Burnley, sending the Magpies into Tuesday's match at Benfica on the back of a clean sweep.
Newcastle United XI A: Nick Pope, Matt Bondswell, Dan Burn (c), Sven Botman, Emil Krafth, Jonjo Shelvey, Joelinton, Bruno Guimarães, Allan Saint-Maximin, Matt Ritchie, Jacob Murphy
Newcastle United XI B: Karl Darlow, Matt Targett, Paul Dummett, Jamaal Lascelles (c), Kieran Trippier, Sean Longstaff, Elliot Anderson (sub Matty Longstaff), Joe Willock, Ryan Fraser, Callum Wilson, Miguel Almirón (sub Santiago Muñoz)
Subs not used: Alex Murphy, Jay Turner-Cooke