Here's our guide to where and when the Magpies' internationals will be playing in September:
Nick Pope and Kieran Trippier
The United duo are part of Gareth Southgate's England squad for their UEFA Nations League games against Italy and Germany as the Three Lions prepare for this winter's World Cup finals. The pair have been in superb form for Newcastle this season, and Pope will be looking to add to his eight appearances for his country, with Trippier having already amassed 37 caps.
Friday 23rd SeptemberItaly vs EnglandSan SiroKick-off 7:45pm BST
Monday 26th SeptemberEngland vs GermanyWembley StadiumKick-off 7:45pm BST
Fabian Schär
Centre back Schär is part of the Switzerland squad for their UEFA Nations League games against Spain and the Czech Republic, with the Magpies defender currently sat on 71 caps and eight goals for his country.
Saturday 24th SeptemberSpain vs SwitzerlandEstadio La RomaredaKick-off 7:45pm BST
Tuesday 27th SeptemberSwitzerland vs Czech RepublicKybunparkKick-off 7:45pm BST
Alexander Isak
Recent arrival Isak had been called up to the Sweden squad for their UEFA Nations League double-header against Serbia and Slovenia later this month, but the former Real Sociedad frontman - who has nine goals to show from his 37 senior outings for his country to date - is now set to return to Tyneside after picking up a minor injury.
Jamal Lewis
Full back Lewis is yet to make a Premier League appearance for the Magpies this term, but has been named in the Northern Ireland squad for their UEFA Nations League group games against Kosovo and Greece. The former Norwich man currently has 23 caps to his name.
Saturday 24th SeptemberNorthern Ireland vs KosovoWindsor ParkKick-off 5pm BST
Tuesday 27th SeptemberGreece vs Northern IrelandGeorgios Kamaras StadiumKick-off 7:45pm BST
Bruno Guimarães
The United midfielder, now a regular in the Brazil side, has been named in the Selecao squad for their two pre-World Cup friendlies in France. Tite's men face Ghana and Tunisia as they continue their preparations for November's tournament in Qatar, with Guimarães looking to add to his tally of eight caps and one goal.
Friday 23rd SeptemberBrazil vs GhanaStade OceaneKick-off 7:30pm BST
Tuesday 27th SeptemberBrazil vs TunisiaParc des PrincesKick-off 7:30pm BST
Miguel Almirón
Winger Almirón has been called up by Paraguay, who are also opting to play their two friendlies on European soil this month. The 28-year-old - who has 41 international caps and three goals to his name - could line up against the UAE in Austria before his side take on Morocco in Seville.
Friday 23rd SeptemberParaguay vs UAEStadion Wiener NeustadtKick-off 5pm BST
Tuesday 27th SeptemberParaguay vs MoroccoEstadio Benito VillamarinKick-off 8pm BST
Chris Wood
Forward Wood, meanwhile, has a lengthy trip to come, with New Zealand set to take on Australia in both home and away fixtures in September. The All Whites' leading marksman could add to his record tally of 33 goals when his nation take on the Socceroos in both Brisbane and Auckland.
Thursday 22nd SeptemberAustralia vs New ZealandSuncorp StadiumKick-off 11am BST
Sunday 25th SeptemberNew Zealand vs AustraliaEden ParkKick-off 4am BST
Ryan Fraser
Wideman Fraser has been called up for Scotland's upcoming UEFA Nations League fixtures against Ukraine and the Republic of Ireland. Former United coach Steve Clarke has opted to include the 28-year-old in his roster for the three games, which includes both home and away matches against Ukraine.
Wednesday 21st SeptemberScotland vs UkraineHampden ParkKick-off 7:45pm BST
Saturday 24th SeptemberScotland vs Republic of IrelandHampden ParkKick-off 7:45pm BST
Tuesday 27th SeptemberUkraine vs ScotlandMarshal Jozef Pilsudski StadiumKick-off 7:45pm BST
Alex Murphy
United's young defender Murphy, who is part of Elliott Dickman's second string squad, has received his first international call-up since he joined the Magpies from Galway United in the summer. Murphy could line up for the Republic of Ireland Under-19s in their European Championship qualifiers against Gibraltar, Wales and Hungary.
Wednesday 21st SeptemberRepublic of Ireland Under-19s vs Gibraltar Under-19sCentral ParkKick-off 4pm BST
Saturday 24th SeptemberWales Under-19s vs Republic of Ireland Under-19sNantporth StadiumKick-off 1pm BST
Tuesday 27th SeptemberHungary Under-19s vs Republic of Ireland Under-19sNantporth StadiumKick-off 6pm BST
Elliot Anderson and Lucas De Bolle
Magpies youngsters Anderson, who has broken into Eddie Howe's first team this term, and De Bolle, currently on loan at Hamilton in Scotland, were both included in the Scotland Under-21 squad for their friendly double-header against Northern Ireland - but Anderson, who signed a new long-term deal at St. James' Park this week, has had to to withdraw from the squad with an injury.
Thursday 22nd SeptemberNorthern Ireland Under-21s vs Scotland Under-21sDanny Blanchflower StadiumKick-off 2:30pm BST
Sunday 25th SeptemberScotland Under-21s vs Northern Ireland Under-21sThe SMiSA StadiumKick-off 2pm BST
