The Magpies’ youngsters eliminated the Silkmen in the Second Round of the competition last time out, drawing 1-1 at St. James’ Park before winning a tense penalty shootout.
They head to Moss Rose on Tuesday, 3rd September, with kick-off at 7.45pm.
For the third season in a row, United will take on just one League One side in the opening round. This time, it’s Shrewsbury Town, with a trip to the Montgomery Waters Meadow scheduled for Tuesday, 8th October (7.30pm kick-off).
The Magpies round off their Group D fixture list against Port Vale, heading to the Potteries on Tuesday, 12th November for a 7.45pm kick-off. United met the Valiants in the same round of the 2017/18 competition, losing 1-0 at Vale Park.
Ticketing details will be confirmed in due course.