The Spaniard hit a hat-trick against Southampton, sandwiched between the winner against Leicester and the opening goal of last weekend's draw against Brighton & Hove Albion.
Nobody in the top flight scored more times during the month than Pérez, while April also saw him break into the top ten of Newcastle's all-time Premier League top goalscorers list.
The 25-year-old is nominated alongside Chelsea's Eden Hazard, Liverpool's Jordan Henderson and Mohamed Salah, Manchester City defender Aymeric Laporte, Southampton's Shane Long, Leicester's Jamie Vardy and Burnley's Chris Wood.
Supporters can vote for Pérez to win the EA Sports-sponsored award here. Voting closes at 6pm (BST) on Thursday.