The Magpies have won the trophy 39 times since it was first played for in 1884 - but haven't done so since 2018, when a side including Dan Barlaser, Cal Roberts and Curtis Good beat Morpeth Town 3-1.
Ben Dawson's team have beaten Newcastle Blue Star, Bedlington Terriers and Ashington to set up the showpiece clash against Blyth Town, who have seen off Whitley Bay, Morpeth and Newcastle Benfield.
Kick-off is at 7:30pm BST and the Northumberland FA has confirmed that a pay-at-the-gate system will be in operation on the evening, with tickets priced at £8 for adults, £4 for concessions and £2 for under-18s. Supporters will be granted access to the East Stand at St. James' Park via turnstiles 39-47.
But supporters who can't make the match will be able to watch for free on NUFC TV, while the game will also be streamed live on Newcastle United's official YouTube channel.
James Huntley, Jay Turner-Cooke and Cathal Heffernan are among the Magpies youngsters who will be looking to showcase their skills to a global audience.
Can Newcastle lift the trophy for the first time in six years? Watch live on NUFC TV or YouTube from 7:30 BST on Tuesday.