The Magpies host Patrick Vieira's side in round three of the Carabao Cup on Wednesday, 9th November (kick-off 7.45pm GMT), with the game live on Sky Sports.
With a capacity crowd expected, the attendance is set to surpass the club's current home League Cup record of 49,902 - set in January 1976 as United overcame a 1-0 first leg deficit to beat Tottenham Hotspur 3-1 and set up a trip to Wembley.
The club came close to surpassing the record in October 2016, when 49,042 supporters watched a 6-0 demolition of Preston North End in the fourth round of the competition.
To purchase tickets for future matches, please visit book.nufc.co.uk or call the Box Office on 0344 372 1892.
Official ticket and hotel packages for all Newcastle United home Premier League and cup fixtures are available via club partners SportsBreaks.com. Packages include an official match ticket, plus a minimum one-night stay in a North East hotel, including breakfast.
