United's second-string return to playing action following the international break and target a first victory on home soil this term against a Hammers side who have won their opening three league fixtures.
The young Magpies' unbeaten start to the season ended with a 1-0 defeat against Derby County last month but, after an impressive away win against defending Premier League 2 champions Tottenham Hotspur and a first EFL Trophy victory since 2018 against League Two Bradford City, Harris is keen to build further on bright performances of late.
"We're all keen," the 17-year-old goalkeeper told newcastleunited.com. "We've been training very hard in the build up to this game and we're all really excited to get back into it after a bit of a break.
"It'll be a tough game but I think we are ready to handle good teams like West Ham. It's nice to play at home, not having to travel down south like we've done previously, and we're ready to play.
"It's been a positive start. It would have been nice to remain unbeaten but, overall, it's been strong and it's just about keeping that consistency."
Harris proved the hero in Newcastle's Bristol Street Motors Trophy victory against Bradford over a fortnight ago, saving two penalties in the shoot-out triumph against the Bantams following a 2-2 draw at the University of Bradford Stadium.
The teenage shot-stopper, who signed his first professional contract with his boyhood club last summer, reflected positively on an impressive display both individually and collectively.
Harris, who joined United's Academy in 2017, added: "Going down to Bradford, you know what you're going to expect in facing a senior team but I think we played really well throughout the whole game, putting up a good fight against a good side.
"I made two saves in the penalty shoot-out to win the game and Josh (Donaldson) scored the winning penalty. It was a great win and I think we can take a lot of credit for not giving up and coming away with a positive result.
"I watched it back a few times to keep reliving the moment and keeps me motivated to try and do the same in the upcoming games, whether that's a penalty shoot-out or during a game.
"Visualisation is a very important aspect of the game, going out onto the pitch before kick-off and thinking about how the game would pan out. I could only think positive thoughts about the penalties so it was really good."
Admission for Friday's Premier League 2 visit of West Ham United is free for Newcastle United season ticket holders, otherwise it's £3 for adults and £1 concessions.
The game will also be streamed live, for free, on the Official Newcastle United App, which can be downloaded on the App Store or Google Play.